bio-crispr-screens-screen-qc
lilinji/GeneTind-Life-SkillsQuality control for pooled CRISPR screens covering library representation, Gini index, log-skew, replicate Pearson and Spearman concordance, essentialome…
Scores out of 100 · grade B+
2026-08-22Works
40% of the score100/100
- Loads cleanly: valid frontmatter, required fields present, no dangling references.
Maintained
25% of the score94/100
- no commits in the last 12 weeks
- no license file
Adopted
20% of the score13/100
- 8 stars on the source repo.
Documented
15% of the score91/100
- 2,965 words with worked examples.
- Ships 2 bundled files.
Install
npx skills add lilinji/GeneTind-Life-Skills/bio-crispr-screens-screen-qcWhat the check found
| Finding | What it means |
|---|---|
| No license | The repository ships no license file, so the reuse terms are unclear. |
What it says it does
Quality control for pooled CRISPR screens covering library representation, Gini index, log-skew, replicate Pearson and Spearman concordance, essentialome precision-recall AUC against CEGv2 (Hart 2017), Cas9 cut-toxicity diagnostics, copy-number amplicon detection (Aguirre 2016 / Munoz 2016), bottleneck propagation through plasmid pool, infection, selection, and endpoint stages, MOI verification, and DepMap-style screen-quality scoring. Use when assessing screen quality before hit calling, deciding whether to repeat or rescue a screen, diagnosing low-confidence hits, choosing between MAGeCK / BAGEL2 / Chronos based on quality grade, picking a normalization strategy from QC signatures, or evaluating whether an in-vivo screen retained adequate library complexity.
Also in lilinji/GeneTind-Life-Skills
| Artifact | Score | What the check found | Type | Reach | Last commit |
|---|---|---|---|---|---|
| arboretolilinji/GeneTind-Life-Skills | No license | Skill | 8 stars | today | |
| aws-cdk-developmentlilinji/GeneTind-Life-Skills | No license | Skill | 8 stars | today | |
| bidslilinji/GeneTind-Life-Skills | No license | Skill | 8 stars | today | |
| adaptyvlilinji/GeneTind-Life-Skills | No license | Skill | 8 stars | today | |
| analyze-fastalilinji/GeneTind-Life-Skills | No license | Skill | 8 stars | today | |
| ancestry-risk-profilerlilinji/GeneTind-Life-Skills | No license | Skill | 8 stars | today |
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