bio-clinical-databases-somatic-signatures

lilinji/GeneTind-Life-Skills

SkillLoads cleanly

Extracts and assigns COSMIC v3.4 mutational signatures (86 SBS / 11 DBS / 18 ID / 21 CN / 16 SV) from somatic VCFs using SigProfilerSuite, MutationalPatterns,…

Scores
out of 100 · grade B+

2026-08-22

Works

40% of the score

100/100

Loads cleanly: valid frontmatter, required fields present, no dangling references.

Maintained

25% of the score

94/100

no commits in the last 12 weeks
no license file

Adopted

20% of the score

13/100

8 stars on the source repo.

Documented

15% of the score

91/100

3,654 words with worked examples.
Ships 3 bundled files.

Loads cleanly. Every structural check Claude Code needs to register this passed. Last commit today.

Install

npx skills add lilinji/GeneTind-Life-Skills/bio-clinical-databases-somatic-signatures

What the check found

Every finding on this listing, and what each one means for whether it loads.
Finding	What it means
No license	The repository ships no license file, so the reuse terms are unclear.

What it says it does

Extracts and assigns COSMIC v3.4 mutational signatures (86 SBS / 11 DBS / 18 ID / 21 CN / 16 SV) from somatic VCFs using SigProfilerSuite, MutationalPatterns, MuSiCal mvNMF, SigNet, or HRDetect. Use when characterizing DNA-damage etiology (BRCA1/2 HRD, MMR-D, POLE, APOBEC3A, UV, tobacco, aflatoxin, 5-FU/SBS17b, platinum, colibactin SBS88), routing PARP inhibitor decisions, or auditing de novo extraction vs refit choice for cohort size.

Every number above came out of reading the file and its repository. Nothing is a judgement call, nothing is a model’s opinion, and nothing can be paid for. The full method is published. Source last committed 2026-08-21.

Also in lilinji/GeneTind-Life-Skills

Other artifacts published from the same repository.
Artifact	What the check found	Type	Reach	Last commit
arboretolilinji/GeneTind-Life-Skills	No license	Skill	8 stars	today
aws-cdk-developmentlilinji/GeneTind-Life-Skills	No license	Skill	8 stars	today
bidslilinji/GeneTind-Life-Skills	No license	Skill	8 stars	today
adaptyvlilinji/GeneTind-Life-Skills	No license	Skill	8 stars	today
analyze-fastalilinji/GeneTind-Life-Skills	No license	Skill	8 stars	today
ancestry-risk-profilerlilinji/GeneTind-Life-Skills	No license	Skill	8 stars	today

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