bio-causal-genomics-genomic-sem
lilinji/GeneTind-Life-SkillsFits structural equation models to GWAS summary statistics using GenomicSEM (Grotzinger 2019), including common-factor models, confirmatory factor models,…
Scores out of 100 · grade B+
2026-08-22Works
40% of the score100/100
- Loads cleanly: valid frontmatter, required fields present, no dangling references.
Maintained
25% of the score94/100
- no commits in the last 12 weeks
- no license file
Adopted
20% of the score13/100
- 8 stars on the source repo.
Documented
15% of the score91/100
- 4,656 words with worked examples.
- Ships 3 bundled files.
Install
npx skills add lilinji/GeneTind-Life-Skills/bio-causal-genomics-genomic-semWhat the check found
| Finding | What it means |
|---|---|
| No license | The repository ships no license file, so the reuse terms are unclear. |
What it says it does
Fits structural equation models to GWAS summary statistics using GenomicSEM (Grotzinger 2019), including common-factor models, confirmatory factor models, ESEM, common-factor GWAS with Q_SNP heterogeneity, multivariate Wald tests, and stratified GenomicSEM partitioned heritability. Reconciles results against MTAG multi-trait analysis. Handles sample overlap via the LDSC sampling-covariance matrix, identifies and resolves Heywood cases, and verifies model fit with CFI / RMSEA. Use when modeling latent genetic architecture across correlated traits, running multivariate GWAS on a shared factor, distinguishing factor-mediated from trait-specific SNP effects, or comparing GenomicSEM common-factor results against MTAG when both depend on accurate sampling covariance.
Also in lilinji/GeneTind-Life-Skills
| Artifact | Score | What the check found | Type | Reach | Last commit |
|---|---|---|---|---|---|
| arboretolilinji/GeneTind-Life-Skills | No license | Skill | 8 stars | today | |
| aws-cdk-developmentlilinji/GeneTind-Life-Skills | No license | Skill | 8 stars | today | |
| bidslilinji/GeneTind-Life-Skills | No license | Skill | 8 stars | today | |
| adaptyvlilinji/GeneTind-Life-Skills | No license | Skill | 8 stars | today | |
| analyze-fastalilinji/GeneTind-Life-Skills | No license | Skill | 8 stars | today | |
| ancestry-risk-profilerlilinji/GeneTind-Life-Skills | No license | Skill | 8 stars | today |
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